Florian
Ion Tiberiu Petrescu
IFToMM, Romania
E-mail: fitpetrescu@gmail.com
Relly
Victoria Virgil Petrescu
IFToMM, Romania
E-mail: rvvpetrescu@gmail.com
Submission: 1/4/2019
Revision: 11/24/2020
Accept: 12/1/2020
ABSTRACT
In general, life is
only possible in the presence of oxygen in a form that can be easily absorbed
by the body. In the case of humans, the lungs have as their main task the
provision of the oxygen necessary for the body to carry out daily activities.
The lung is a paired organ located in the chest cavity, a fibro-elastic organ
capable of altering your volume during breathing (inspire and expire). The
weight of a lung varies between 800 and 1,000 grams, of which more than 50% is
blood. The air reaches the lungs through a pipeline system consisting of
Nazo-pharynx, larynx, trachea, bronchi, and bronchiole. The role of the piping
system is to heat and dampen the air or to capture and remove foreign inhaled
particles. The channel system decreases in diameter after each branch - from
the trachea and the large bronchi to the bronchiole with a diameter of less
than one millimeter. The lung consists of over 30 different cell types. Trachea
and large bronchi are taped by a mucous layer containing multiple cell types: ciliary
cells - provides mucus movement, caliciform cells - secretes mucus, basal cells
- plays a role in regeneration and neuro-ectodermic cells - ensures the
secretory function of the lungs. In the chorion (the deep layer beneath the
mucosa) there are cells involved in the defense processes - lymphocytes, mast
cells, eosinophils or neutrophils.
Keywords: Human body; Human body's lungs; Physiopathology; Anti-aging
1.
INTRODUCTION
In general, life is only possible in the presence of oxygen in a form that can be easily absorbed by the body. In the case of humans, the lungs have as their main task the provision of the oxygen necessary for the body to carry out daily activities.
The lung is a paired organ located in the chest cavity, a fibro-elastic organ capable of altering your volume during breathing (inspire and expire). The weight of a lung varies between 800 and 1,000 grams, of which more than 50% is blood.
The lung develops gradually during intra-uterine life. During the first month of pregnancy, there are two bronchial buds that will develop in the primary bronchi. Then every week these buds will divide, reaching 28 generations (branching) of the bronchi - the next bronchial tree after 28 weeks. After birth the number of alveoli increases (up to the age of 3 years), then matures functionally, becoming mature alveoli (up to the age of 8).
The lungs are the main organs of breathing. There are two lungs (lance and right) located in the chest cavity, each covered by visceral pleura. The lungs have the form of half a cone. Their color varies with age; to the fetus, red-brown, to the gray-to-gray child, to the darker adult more or less closed. The weight of the lungs is 700 g for the right lung and 600 g for the left lung.
The total lung capacity is 5000 cm³aer. Total lung consistency is classic, sponge. The vertical diameters are 22 cm, anteroposterior to the base of 18-20 cm and transversally at the base of 9-10 cm. (The right diameter of the lung is smaller than the left, but the other diameters are larger).
The external face of the lungs is convex and comes in relation to the ribs. On this face, there are deep ditches called scree, which distribute the lungs in the lobes. On the external face of the right lung, there are two skulls - one oblique (main) and another horizontal, which begins at the middle of the oblique fission. These two scions divide the lungs into three lobes (upper, middle and lower). On the external face of the left lung, there is a single fissure (oblique fissure), which divides the left lung into two lobes (upper and lower).
The side face is flat and comes in contact with the mediastinal organs. On this face, closer to the posterior edge of the lungs, there is the pulmonary hill where the vessels, the nerves, and the main bronchus enter or leave the lung.
The base of the lungs is concave and comes in relation to the diaphragm. The tip of the lung lifts up the first coast and comes in relation to the organs at the base of the neck. The anterior sharp edge is located behind the sternum, and the posterior, rounded, is in relation to the backbone and posterior extremity of the ribs.
The air reaches the lungs through a pipeline system consisting of Nazo-pharynx, larynx, trachea, bronchi, and bronchiole.
The role of the piping system is to heat and dampen the air or to capture and remove foreign inhaled particles.
The
channel system decreases in diameter after each branch - from the trachea and
the large bronchi to the bronchiole with a diameter of less than one millimeter
(Aversa et al., 2018a-b, 2017a-b, 2016a-n; Aljohani & Desai, 2018;
Alexander & Wang, 2018; Apicella et al., 2018 a-c; Marquetti & Desai,
2018; Armah, 2018; Wilk et al., 2017; Babaev et al., 2010; Buzea et al., 2015;
Petrescu et al., 2015; Petrescu, 2008-2009; Abdul-Razzak et al., 2012; Ajith et
al., 2009; Atasayar et al., 2009; Ahmed et al., 2011; Covic et al., 2007;
Willis, 1953-1954, 1957; Ha, 2010; El-Gendy, 2009; Enstrom, 2014; Hansen, 2014;
Rath, 1990, 2003; Yilmaz, 2006; Ravnskov, 2009; Kunutsor, 2016; Hickey, 2007;
Choudhury & Greene, 2018; Choudhury, 2018).
2.
METHODS AND MATERIALS; THE STRUCTURE
OF THE LUNGS AND FUNCTIONALITY
The lungs consist of: the bronchial tree, the lobules (pyramidal formations located at the last branches of the bronchial tree), the branches of the pulmonary and bronchial vessels, nerves and lymph, all contained in connective tissue.
The bronchial tree.
The main bronchus, penetrating into the lung through the hill, is divided intrapulmonary to the right in three lobar bronchi (upper, middle and inferior), and to the left in two lobar bronchi (upper and lower).
The lobar bones then divide into segmental bronchi that provide aeration of the bronchopulmonary segments (anatomical and pathological units of the lungs). They have their own limitations, aeration, vascularization, and pathology. The right lung has 10 segments, the left 9.
Segmental bronchi are divided into lobular bronchiole which serves the pulmonary lobules, the morphological units of the lung, the pyramidal form, with the base to the periphery of the lung and the peak to the hill.
The lobular bronchiole, in turn, branches into the respiratory bronchiole from which the alveolar ducts are terminated by alveolar sacs.
The walls of the alveolar sachets are compartmentalized into the lung alveoli.
Respiratory bronchi, together with the formations derived from them (alveolar ducts, alveolar sacs, and pulmonary alveoli) form pulmonary acinus. Acin is the morpho-functional unit of the lung.
The structure of the bronchial tree also changes. Lobar bronchi have a structure similar to the main bronchi. Segmental bronchial also have a cartilaginous skeleton fragmented (cartilage islands), instead, the lobular and respiratory lobes completely lose cartilaginous skeleton.
The lobular and respiratory bronchioles have a fibro-elastic wall over which smooth muscle fibers are disposed. In the alveolar duct walls, we encounter only the fibro-elastic membrane lined with epithelium.
The pulmonary alveoli are in the form of a small, extremely thin sachet adapted to gaseous exchanges. On a fibro-elastic membrane, there is an alveolar epithelium with a double function: phagocytic and respiratory.
There are about 75-100 million alveoli, with an area of 80-120 m².
A rich perialveolar capillary network is found around the alveoli, which together with the alveolar walls form the alveolar-capillary barrier, in which structure we mention the alveolar epithelium, the basal fibro-elastic membrane of the alveoli, the basal membrane of the capillary and capillary endothelium. At the level of this barrier, there are gas exchanges between the alveoli and the blood.
The lung consists of over 30 different cell types. Trachea and large bronchi are taped by a mucous layer containing multiple cell types: ciliary cells - provides mucus movement, caliciform cells - secretes mucus, basal cells - plays a role in regeneration and neuro-ectodermic cells - ensures the secretory function of the lungs. In the chorion (the deep layer beneath the mucosa) there are cells involved in the defense processes - lymphocytes, mast cells, eosinophils or neutrophils. Respiratory bronchiole and terminal channels (the last ramifications of the bronchial tree, open in alveolar bags) contain Clara cells - secret surfactant and mucus (Fig. 1).
Figure 1: The structure of the lungs
Source:
https://www.scientia.ro/images/stories/articles/2012/aprilie/17/plamani_1.jpg
1-aperture; 2-falciform
ligament; 3-fibrous pericardium; 4-lower lobe of the left lung; 5-lower lobe of
the right lung; 6-the left liver lobe; 7-line of the left pleura reflection;
8-line of the right pleura reflection; 9-middle lobe of the right lung;
10-fissure oblique; 11-oblique fissure of the right lung; 12-pleura covering the
pericardium; 13-left and right pleura in contact; 14-the right liver lobe;
15-the upper lobe of the left lung; 16-the upper lobe of the right lung; 17-the
transversal fissure of the right lung.
2.1.
Vascularization
of the lungs
The
lungs have a double vasculature: nutritional and functional.
1)
Nutritional vascularisation is provided by the
bronchial arteries, branches of the thoracic aorta, which bring oxygen to the
blood. The bronchial arteries enter the lung through the hill and accompany the
bronchial shaft, reaching only to the respiratory bronchiole, ending in the
capillary network, from which the bronchial veins that carry the blood with CO2
in the azygos system start, ending in the superior cava. Nutritional
vascularization of the lung makes the circulation large.
2)
Functional vasculature belongs to small circulation. It
begins with the pulmonary trunk that originates in the right ventricle. The
lung trunk brings blood loaded with CO2 to the lung. After a short tract, it
splits into the left and right pulmonary artery, each penetrating the lung
through the hill. In the lung, the pulmonary arteries divide into branches that
accompany the branches of the bronchial shaft up to around the alveoli, where
they form the perialveolar capillary network. At this level, the blood yields
CO2 and gets O2. From the capillary network, the pulmonary veins start (two for
each lung). They come out of the lung through the hill and go to the left
atrium.
Because
the vascularization of the lungs is dual - nutritional and functional, the
nutritional is provided by the bronchial arteries, while the functional one is
the pulmonary artery (small circulation).
Functional
vasculature starts from the right ventricle - the pulmonary artery, with
non-oxygenated blood. It splits into two branches for each lung and branches up
to the formation of a pulmonary capillary network (very small diameter
vessels). The main role of the capillary network is to participate in the
exchange of gas between air and blood. All branches of the mesh unite and form
the pulmonary veins (they carry oxygenated blood) that flow into the left
atrium.
The
functional unit of the lung is the pulmonary acin (or alveolar sac) made up of
pulmonary alveoli. They contain two types of cells - type I pneumocytes and
type II pneumocystis (the second type of surfactant). In addition to these
cells, macrophages can also be found. In total, the two lungs contain
approximately 300 million lung alveoli that provide for the exchange of
respiratory gas between the blood and the atmospheric air. The main role in
this exchange lies with the alveolar membrane. This is an air-blood barrier
consisting of type I and II pneumocytes and surfactant in the alveolar part,
and on the other side of the membrane and capillary endothelium.
The
thickness of the membrane is only 0.5 micrometers and ensures rapid gas
exchange (between blood and air). The surfactant I have mentioned is a fluid
whose role can be easily understood - compare the pulmonary alveolus with a
rhythmically inflamed rubber bubble (respiratory movements), and the surfactant
that holds the alveolus open with the talcum powder inside the balloon prevents
the rubber from sticking. So, the role of the surfactant is to prevent
collapsing the pulmonary alveolus.
The
lungs are covered by a membrane - the pleura (Fig. 2). It consists of two
foils, a visceral one that adheres to the surface of the pulmonus and a
parietal one that adheres to the chest wall. Between the two sheets there is an
amount of fluid that plays a role in the respiratory movements. The amount of
fluid that is found between the pleura leaves is 15 ml, but within 24 hours 600
ml of fluid is secreted, which means that the pleural fluid is renewed several
times in a single day.
Figure 2: Pleura is a membrane covering the lungs to protect them.
Source:
https://www.scientia.ro/images/stories/articles/2012/aprilie/17/plamani_2.jpg
1-branches of the main
right bronchus; 2-branches of the right pulmonary artery; 3-seam of the azygos
vein; 4-seam of the first rib; 5-seam for subclavian artery; 6-subclavian vein
ditch; 7-seam for superior cava vein; 8-esophageal aria and trachea;
9-pulmonary right veins; 10-fissure transverse.
Pulmonary
ventilation is a dynamic process that ensures air penetration into the airways.
Inspiration (air intake) is an active, energy-consuming process, carried out by
the contraction of the inspiring muscles that increase the volume of the chest.
The lung follows faithfully the movements of the chest. Exhale - a passive
process, is achieved by relaxing the respiratory muscles, which leads to a
decrease in the volume of the chest.
The
air penetrates into the lungs due to differences in pressure between
atmospheric air and air in the lungs. The speed of movement in the airways is
30 cm/sec and decreases to 0 in the alveoli. Of the inspired air volume, only
two-thirds participate in gaseous exchanges, the rest remains on the trachea or
in the bronchi (a dead functional space).
Respiratory
volumes can be measured with an apparatus called spirograph. It measures vital
capacity (CV) - consisting of current volume (VC), spare inspiratory volume
(VIR), and spare expiratory volume (VER).
VC -
is the volume of air that penetrates into the lungs during normal, resting
respiration. This is 500 ml of air, out of which only 350 ml reach the
territories where gas exchanges are made.
VIR -
is the maximum volume of air that can be inserted into the lungs after a normal
inspiration. Its value is 1200-1,500 ml of air and together with VC forms the
inspiratory capacity of the lung (CI).
VER -
is the maximum volume of air that can be removed from the lung after a normal
exhalation and is 1200 ml.
In
addition to these volumes, there is also the residual volume (VR). VR is the
volume of air that is always in the lungs and can not be removed, just renewed.
The VR is 1200 ml and together with the CV form the total pulmonary capacity
(CPT). Residual volume is of great importance in legal medicine. With the help
of residual volume, it can be determined whether a child was born dead or died
after birth - VR penetrates into the lungs after the first breath. If the baby
is born dead his lungs will not float in the water, but if he breathes after
birth, the lungs will remain at the surface of the water.
Breathing
is a complex process consisting of three phases - pulmonary respiration, airway
transport, and cellular respiration (cell-to-blood gas exchange).
Alveolocapillary
membrane gas changes (pulmonary respiration) are governed by the physical laws
of diffusion - the Boyle-Mariotte law (gas pressure at the same temperature is
inversely proportional to volume), the Gay-Lussac law (the volume of a gas
increases once with temperature if the pressure remains constant).
The
consequence of pulmonary ventilation is the permanent intake of oxygen. Oxygen
arrived in the pulmonary alveolar is absorbed into the capillary blood. One
minute passes 200 ml of oxygen from the alveolar air into the capillary blood.
Due to
metabolic processes in the human body, large amounts of acids are produced.
Non-volatile acids are eliminated through the kidneys, and volatile ones are
eliminated through the lungs - CO2. It will be permanently removed externally
through the ventilation process. The rate of carbon dioxide removal is 200 ml
per minute.
Breathing
is a nervous and humorous process. Although it can be controlled voluntarily,
breathing is regulated by reflex and humorous mechanisms - you cannot kill
yourself if you keep your breath. Breathing is regulated by the respiratory
centers located in the brain.
In
addition to nervous centers, there are a number of mechanisms that regulate
breathing. These are the pressure receptors. They respond to changes in blood
pressure (baroreceptors) or respiratory gases (chemoreceptors).
The
lung, like most organs, has a major function - respiratory function, but also
other side functions: antitoxic, metabolic or depot function.
2.2.
Antitoxic
function
By
inhalation are inhaled particles that can harm the body: powders, bacteria, toxic
gases. Particles with a larger diameter are retained in the mucus of the
trachea or bronchi, but those with a small diameter - less than 3 micrometers,
reach the pulmonary alveoli. All particles suspended by the mucus are removed
with it through the movements of the cilia. In addition to ciliary transport,
the reflex of a cough and sneezing intervenes, which contributes to the
elimination of contaminated secretions.
Particles in the alveoli are
phagocytic by macrophages. Those that get rid of macrophages are in contact
with the surfactant in the alveoli. It contains enzymes (lysozyme, esterase),
interferon or Ig A antibodies that destroy bacteria and prevent colonization of
the alveoli (sterile areas normally).
In
addition to protecting the body from bacteria, the lungs can remove some toxins
from the body. These are volatile substances that easily pass through the
alveolar-capillary membrane - it produces a breathing halo. This can remove
alcohol, urea, and nitrous oxide.
2.3.
Metabolic
function and immune function of the lungs
The
lung is involved in glucose, lipid, protein metabolism and in the metabolism of
some hormones or chemical mediators. The lung determines the conversion of
angiotensin I to angiotensin II - a substance with strong vasoconstriction
effects. Lungs synthesize a wide range of substances with different effects in
the body - prostacyclin, thromboxanes or leukotrienes.
Later,
it was found that the lungs produced various types of leukocyte cells needed to
protect the body, thereby enhancing immune function.
2.4.
Accessories
features
The
lungs can store up to 12% of the body's blood volume under resting conditions -
the blood vessel function, which they send in circulation when needed. In
addition to the storage function, the lungs are also involved in maintaining
the hydro-electrolytic balance. They can remove large amounts of water, heat
and carbon dioxide.
Together
with the bone system and the liver, the lungs are true tanks of blood, can keep
a large amount for an unlimited, shorter or a very long time after the needs of
the body. The same is done for the liver, but only for short periods of time
for certain blood vessels. Bones that produce blood in their marrow can store
large amounts of blood, and can also regenerate it so that the lungs form
alongside the bone system in a true blood-capacitor reservoir, absolutely
necessary for the human body. When the amount of blood and water in the body
decreases, the body begins to age and lose energy from water and transported
through the blood. In order to delay the human aging process, it is therefore
absolutely necessary to keep both lungs healthy at maximum functional capacity
as well as the bone system for a long time in our lives.
3.
RESULTS AND DISCUSSION
Breathing
is the exchange of O2 and CO2 between the body and the environment. This
exchange takes place in three stages:
·
pulmonary stage - external breathing
·
blood stage - gas transport
·
Tissue Stage - External Breath
True
breathing, in the strict sense of the word, is the tissue, while the first two
stages only provide the breathing of the breathing gases from the internal
environment.
3.1.
The
pulmonary stage realizes the first moment of gaseous exchanges.
In the
alveolar-capillary membrane, O2 passes from the alveolar air into the blood,
and CO2 in the opposite direction. The organs of external breathing are the
lungs and chest (passive organs) and respiratory muscles (active organs).
Respiratory
movements occur as a result of the rhythmic intake and outflow of respiratory
muscles. These movements take place in two phases: inspiration and expiration.
Inspiration
is an active process through which atmospheric air penetrates the lungs. The
main inspiring muscle is the diaphragm. By contraction, the diaphragm descends
flattens and increases the vertical diameter of the chest box. Apart from the
diaphragm, inspiration is also produced by external intercostal muscles.
Expiration
is the act by which the air leaves the lungs. The only muscles involved in the
expiration are internal intercostals.
The
two phases of pulmonary respiration are successively performed without a break
with a resting frequency of 14-16 cycles/minute in the man and 18 breaths per
minute in a woman.
Neuro-moral regulation of lung breathing
By
regulating breathing, it is commonly understood to regulate fan movements and
fan flow.
3.2.
Fan
flow rates vary by frequency and amplitude of respiratory movements
The
nervous regulation of ventilation is achieved by the intervention of the
respiratory centers. They provide automatic breathing control.
There
are primary respiratory centers located in the bulb and accessory respiratory
centers located at the deck level, represented by the 2/3 hindpaw center and
the pneumotoxic center of the previous 1/3.
The
activity of bulb-pontin nervous centers is altered both in intensity and
frequency, under nerve and humoral influences.
Nervous
influences can be of two kinds:
·
direct, encephalic nerve centers or other neighboring
centers;
·
reflexes, from receptors spread throughout the body.
Direct
cortical nerve influences allow voluntary control of ventilator movements
within certain limits. They explain changes in breathing in emotional states as
well as respiratory conditional reflexes.
Hypothalamic
centers alter the frequency of breathing according to ambient temperature.
Reflex
influences can come from the totality of intero-, extero- and proprioceptors in
the body.
The
main respiratory reflexes are initiated at the level of the respiratory and
cardiovascular devices.
The
humorous regulation of breathing is due to the influences exerted on the
respiratory centers by a number of substances. The most important role in the
humoral regulation of breathing plays the breathing gases CO2 and O2.
The
essential role of CO2 and therefore this substance has been called respiratory
hormone. It acts directly on the centers. The increase in PCO2 in arterial
blood only by 0.6 mm HgC from 40 to 40.5) is followed by doubling the pulmonary
ventilator flow rate (from 8 to 16 l / min). Decreasing PCO2 causes breathing
and even stopping it (apnea).
The
role of O2 is also important. The increase in PO2 in arterial blood excites the
chemoreceptors of the reflexogenic regions causing hyperventilation. The
decrease in PO2 acts directly on the centers, but its chemo-reflexive effects
are more important.
3.3.
Blood
stage transports O2 and CO2 through blood.
O2
transport is from the lung to lung tissue O2 diffuses from alveolar air where
its partial pressure is 100 mm Hg in venous blood where PO2 is 40 mm Hg.
O2
transport forms are: physically dissolved in the plasma (0.3 O2%) and
chemically rich in the form of oxyhemoglobin (HbO2) in the proportion of 20O2%
blood.
CO2
transport is made from tissues to the lungs. Carbon dioxide diffuses from
tissues where PCO2 is 46 mm Hg to arterial blood where PCO2 is 40.
The
forms of CO2 transport are:
·
physically dissolved in the plasma as carbonic acid in
a proportion of 3cm³%;
·
chemically bound in the form of 60-60% Na-bicarbonate
in plasma;
·
chemically bound to plasma proteins, Hb and K-bicarbonate
in erythrocytes;
3.4.
Tissue
Stage - Internal Breath
It is
the actual breath of body cells. This process essentially consists of
oxidation-reduction reactions during which hydrogen is combined with oxygen to
give the water and chemical energy that underlies cellular life.
3.4.1.
Sleep apnea syndrome (apnea =
breathing disorder)
Sleep
apnea syndrome (SAS) is a respiratory disorder characterized by frequent and
long breaks of sleep during sleep. Sleep normally causes hypoventilation and
episodes of apnea, but these do not last for more than 10 seconds.
SAS
occurs due to the decrease in diameter in the upper airways (pharynx). These
sick people snore, but when apnea occurs, snoring stops for up to 90 seconds.
During all this time severe hypoxia occurs and the patient wakes up. After a
few seconds, the patient is resting. But apnea episodes appear at a higher
frequency of 200 per night (6-7 hours), making sleep difficult.
The
consequences of SAS are Excessive drowsiness (these patients will never wake
up), memory loss and concentration disorder, high blood pressure and increased
risk of myocardial infarction and stroke.
3.4.2.
Respiratory insufficiency.
a)
2 large types, hypoxemic (I) and hypercapnia (II)
·
Acute (acidosis), chronic (pH N)
·
Diagnosis: Gasometer
·
Treatment:
·
Airways, Breath, Circulation;
·
Controlled Oxygenotherapy (Attention to the
·
hypercapnia!), ventilation (non-invasive - invasive)
·
Treatment and causes
·
Disturbance of gas exchange at the level
b)
alveolar-capillary
·
Decreases PaO2 below normal value = HIPOXEMIA
·
Can increase PaCO2 = concomitantly = hipercarbie
c)
Hypoxemia
·
Normal values - age, oxygen in the air
·
inspired, atmospheric pressure, temperature
·
PaO2 = 100.1 - 0.323 (age in years) ± 5mmHg
o Normal
= 95 - 96 mmHg
o Arterial
saturation = 96%
d)
Hypoxemia
·
Light - 60 - 95mmHg ± 5mmHg
·
Respiratory insufficiency
o Moderate
- 45 - 60 mmHg ± 5mmHg
o Severe
- below 45 ± 5mmHg
e)
Hypercapnia
·
Not influenced by environmental or environmental
parameters age
·
Normal = 35 - 45mmHg
·
Respiratory insufficiency
o PaCO2
above 50 mmHg
f)
General respiratory insufficiency
·
IR is not a disease, but a functional disorder
·
determined by various pathological causes
·
Diagnosis is exclusively laboratory (PaO2, PaCO2)
·
Clinical appearance can accurately suggest the presence
of IR but is not sufficient in the absence of laboratory tests
o Cardiac
insufficiency - Clinically
o Renal
insufficiency - laboratory
3.4.3.
Acute respiratory insufficiency
a)
etiology:
·
Depression of the respiratory center
o Overdose
of drugs (opioids), intoxications
o They
were SNCs
o Unconsciousness
o Progressive
oxygen therapy in patients with chronic hypoventilation
·
Lack of transmission of nerve impulses to mm
respirators
o Marrow
damage
o Myelitis
o Infections
(tetanus, polio, botulism)
o Neuromuscular
diseases (myasthenia gravis, motor neuron diseases, muscular dystrophies):
§
chronic hypoventilation with acute exacerbation, e.g.
respiratory infection
o Polyradiculitis
·
Impact of ventilator mechanics
o Chest
trauma, diaphragm rupture
o Pneumothorax
with valve, hemothorax
o Severe
kyphoscoliosis (usually chronic hypoventilation with acute exacerbation, eg
infection respiratory)
For
centuries, traditional medicine systems around the world have used plants to
treat respiratory diseases.
Even
modern studies have recognized the efficacy of a plant in treating respiratory
diseases, repairing lung damage, and improving lung function.
They
can be used as alternatives to drugs to solve lung problems. Here are some
plants that will clean your lungs and treat respiratory diseases:
b)
Thyme
It is
very strong in the fight against chest congestion. This plant produces powerful
antiseptic essential oils, considered a natural and antifungal antibiotic.
Thyme
also works against acne, making it more effective than expensive creams and
gels.
Thyme
tea has the power to eliminate bacteria and viruses, being a natural remedy
used since antiquity to prevent and treat respiratory tract infections.
c)
Oregano
Although
oregano contains vitamins and nutrients for immunity, its primary benefits are
carvacrol and rosmarinic acid.
These
compounds are naturally decongestant and reduce histamine, having positive
effects on the respiratory tract.
Oregano
oil fights against dangerous bacteria such as golden Staphylococcus, better
than the most powerful antibiotics.
d)
Eucalyptus
Originally
from Australia, eucalyptus is not just for Koala bears! Aborigines, Germans,
and Americans use the eucalyptus refreshing aroma for respiratory ailments and
calming throat irritation. Eucalyptus contains cineol which has many
advantages: it is expectorant, helps relieve cough and congestion and soothes
irritated sinuses.
Eucalyptus
also contains antioxidants that help the immune system during colds and
infections.
e)
Sage
The
leaves of sage emanate a strong flavor, resulting in essential oils. These oils
have multiple benefits for lung problems - cough, sore throat and sinusitis.
Sage
tea is a traditional remedy for a sore throat and cough. It can be administered
internally or externally by inhalation.
f)
Leaves of Patagonia
They
have been used for hundreds of years to soothe a cough and mucous irritation.
Leaves
of Patagonia has antibacterial and anti-microbial, anti-inflammatory and
antitoxic properties.
According
to the studies, the Leaves of Patagonia is favorable against a pulmonary cough,
colds, and irritations. It improves a dry cough and reduces the mucus in the
lungs.
g)
Mint
Mint
and peppermint oil contain menthol - a soothing ingredient known to relax the
muscles of the respiratory tract, decongestant, and a powerful antioxidant.
The plant that keeps your lungs healthy and gets rid of
coughs
h)
Honey of the bear
Bear's
honey is a lichen that resembles lung tissue. Since 1600, the bear's honey has
been used to treat respiratory and lung problems. Bear's honey contains
compounds that are effective for lung health.
i)
Mullet (the candle plant)
Both
flowers and candle leaves are used to prepare an extract that helps to
strengthen the lungs. The candle is used to reduce excess mucus from the lungs,
cleans bronchial tubes and reduces inflammation in the respiratory tract. Tea
can be made from a teaspoon of dried herb to a cup of boiled water.
Alternatively, you can take candy tincture.
Onions
and garlic remain two main active remedies for permanent maintenance of the
lungs.
4.
CONCLUSIONS
In general, life is only possible in the presence of oxygen in a form that can be easily absorbed by the body. In the case of humans, the lungs have as their main task the provision of the oxygen necessary for the body to carry out daily activities.
The lung is a paired organ located in the chest cavity, a fibro-elastic organ capable of altering your volume during breathing (inspire and expire). The weight of a lung varies between 800 and 1,000 grams, of which more than 50% is blood.
The lung develops gradually during intra-uterine life. During the first month of pregnancy, there are two bronchial buds that will develop in the primary bronchi. Then every week these buds will divide, reaching 28 generations (branching) of the bronchi - the next bronchial tree after 28 weeks. After birth the number of alveoli increases (up to the age of 3 years), then matures functionally, becoming mature alveoli (up to the age of 8).
The lungs are the main organs of breathing. There are two lungs (lance and right) located in the chest cavity, each covered by visceral pleura. The lungs have the form of half a cone. Their color varies with age; to the fetus, red-brown, to the gray-to-gray child, to the darker adult more or less closed. The weight of the lungs is 700 g for the right lung and 600 g for the left lung.
The total lung capacity is 5000 cm³aer. Total lung consistency is classic, sponge. The vertical diameters are 22 cm, anteroposterior to the base of 18-20 cm and transversally at the base of 9-10 cm. (The right diameter of the lung is smaller than the left, but the other diameters are larger).
The external face of the lungs is convex and comes in relation to the ribs. On this face, there are deep ditches called scree, which distribute the lungs in the lobes. On the external face of the right lung, there are two skulls - one oblique (main) and another horizontal, which begins at the middle of the oblique fission. These two scions divide the lungs into three lobes (upper, middle and lower). On the external face of the left lung, there is a single fissure (oblique fissure), which divides the left lung into two lobes (upper and lower).
The side face is flat and comes in contact with the mediastinal organs. On this face, closer to the posterior edge of the lungs, there is the pulmonary hill where the vessels, the nerves, and the main bronchus enter or leave the lung.
The base of the lungs is concave and comes in relation to the diaphragm. The tip of the lung lifts up the first coast and comes in relation to the organs at the base of the neck. The anterior sharp edge is located behind the sternum, and the posterior, rounded, is in relation to the backbone and posterior extremity of the ribs.
The
lung, like most organs, has a major function - respiratory function, but also
other side functions: antitoxic, metabolic or depot function.
By
inhalation are inhaled particles that can harm the body: powders, bacteria,
toxic gases. Particles with a larger diameter are retained in the mucus of the
trachea or bronchi, but those with a small diameter - less than 3 micrometers,
reach the pulmonary alveoli. All particles suspended by the mucus are removed
with it through the movements of the cilia. In addition to ciliary transport,
the reflex of a cough and sneezing intervenes, which contributes to the
elimination of contaminated secretions.
Particles
in the alveoli are phagocytic by macrophages. Those that get rid of macrophages
are in contact with the surfactant in the alveoli. It contains enzymes
(lysozyme, esterase), interferon or Ig A antibodies that destroy bacteria and
prevent colonization of the alveoli (sterile areas normally).
In
addition to protecting the body from bacteria, the lungs can remove some toxins
from the body. These are volatile substances that easily pass through the
alveolar-capillary membrane - it produces a breathing halo. This can remove
alcohol, urea, and nitrous oxide.
The
lung is involved in glucose, lipid, protein metabolism and in the metabolism of
some hormones or chemical mediators. The lung determines the conversion of
angiotensin I to angiotensin II - a substance with strong vasoconstriction
effects. Lungs synthesize a wide range of substances with different effects in
the body - prostacyclin, thromboxanes or leukotrienes.
Later,
it was found that the lungs produced various types of leukocyte cells needed to
protect the body, thereby enhancing immune function.
The
lungs can store up to 12% of the body's blood volume under resting conditions -
the blood vessel function, which they send in circulation when needed. In
addition to the storage function, the lungs are also involved in maintaining
the hydro-electrolytic balance. They can remove large amounts of water, heat
and carbon dioxide.
Together
with the bone system and the liver, the lungs are true tanks of blood, can keep
a large amount for an unlimited, shorter or a very long time after the needs of
the body. The same is done for the liver, but only for short periods of time
for certain blood vessels. Bones that produce blood in their marrow can store
large amounts of blood, and can also regenerate it so that the lungs form
alongside the bone system in a true blood-capacitor reservoir, absolutely
necessary for the human body. When the amount of blood and water in the body
decreases, the body begins to age and lose energy from water and transported
through the blood. In order to delay the human aging process, it is therefore
absolutely necessary to keep both lungs healthy at maximum functional capacity
as well as the bone system for a long time in our lives.
For
centuries, traditional medicine systems around the world have used plants to
treat respiratory diseases.
Even modern studies have recognized the efficacy of a plant in treating respiratory diseases, repairing lung damage, and improving lung function. They can be used as alternatives to drugs to solve lung problems. Onions and garlic remain two main active remedies for permanent maintenance of the lungs.
5.
ACKNOWLEDGEMENT
This
text was acknowledged and appreciated by Dr. Veturia CHIROIU Honorific member
of Technical Sciences Academy of Romania (ASTR) PhD supervisor in Mechanical
Engineering.
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